Functional Independence of Layer IV Barrels

Functional independence of layer IV barrels.

Our aim was to investigate the patterns of functional inputs and outputs from individual barrels in the mouse somatosensory cortex, and to test the hypothesis that individual barrels in layer IV are functionally independent of direct inputs from neighboring barrels. In a mouse in vitro slice preparation of the barrel cortex, we recorded voltage-sensitive dye signals evoked in response to micros...

Functional independence of layer IV barrels in rodent somatosensory cortex.

Layer IV of rodent primary somatosensory cortex is characterized by an array of whisker-related groups of neurons, known as "barrels." Neurons within each barrel respond best to a particular whisker on the contralateral face, and, on deflection of adjacent whiskers, display relatively weak excitation followed by strong inhibition. A prominent hypothesis for the processing of vibrissal informati...

Developmental Down-Regulation of LTD in Cortical Layer IV and Its Independence of Modulation by Inhibition

For in vitro LTD to remain viable as a model for synaptic weakening in visual cortical plasticity, it is crucial that it display a critical period for its induction within layer IV. A complicating factor, however, is that LTD in layer IV is modulated by inhibitory postsynaptic potentials (IPSPs); postsynaptic responses characterized as containing IPSPs do not depress in response to 1 Hz afferen...

Factors associated with the functional independence level in older adults

Introduction: Functional independence in old age refers to active presence in daily life. One of the best ways to evaluate the functional independence of elderly is assessing the level of activities. This study aims to determine the status of functional independence in performing instrumental and daily activities as well as its related factors. Methods: This cross-sectional study was cond...

Functional independence measure.